Immunity to Tetanus Vaccination in Pregnant Women in Zanjan Province, Northwest of Iran

Authors

  • Abdolreza Esmaeilzadeh Department of Immunology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. 2Cancer Gene Therapy Research Center, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Farideh Afshari Department of Immunology, Tarbiat Modares University, Tehran, Iran
  • Maryam Erfanmanesh Young Researchers and Elite Club, Zanjan Branch, Islamic Azad University, Zanjan, Iran
  • Safa Tahmasebi Department of Immunology, Tehran University of Medical Sciences, Tehran, Iran
  • Sousan Ghasemi Medical Laboratory of Shaheed Beheshti Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
Abstract:

Background and Aims: Despite the fact that neonatal tetanus has been eradicated all over the world, it is still a significant health problem in some developing countries. The disease can even result in death. This is a worrying problem but it can easily be prevented by vaccination of the mothers. Vaccinating every pregnant woman with, at least, one dose of tetanus toxoid would be an affordable way to protect against neonatal tetanus and would be a step toward eliminating the mortalities that continue to occur due to this preventable disease. The purpose of this study was to evaluate the immunity in pregnant women in Zanjan province in Iran. Materials and Methods: In this cross-sectional study, 576 pregnant women were surveyed. Firs the women's serums were separated. Then tetanus antibody was measured in their serums using Immunoaffinity Chromatography Assay. Results: Results indicated that 95 percent of these pregnant women who had received vaccine had acquired immunity but the remaining 5 percent had no immunization. Conclusions: Not only vaccination is important in women, but effectiveness of vaccination is also vital for successful immunization. It is proposed that more attempts should be made in order to gain affordable immunization.

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volume 5  issue 2

pages  150- 155

publication date 2018-05

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